Treatment of mesial temporal lobe epilepsy using MRgFUS: laboratory feasibility study

Background/introduction Temporal lobe epilepsy remains a significant cause of disabling morbidity. Patients that are refractory to medical treatment are often considered for invasive surgery to remove the epileptogenic focus originating from the structures of the medial temporal lobe. A range of surgical options now exist with varying degrees of efficacy. The goal of any surgical intervention is to minimize disruption of adjacent normal cortical tissue while removing the offending structures. MRgFUS provides the opportunity to perform this task in an elegant fashion. We tested the feasibility of this approach in a cadaveric model.